Noa Moriel on a beach, with a sea turtle resting behind her

Noa Moriel

Machine learning research scientist
PhD in computer science, Hebrew University of Jerusalem

I am interested in the underlying principles that give rise to biological complexity, and in how information emerges through machine learning paradigms. Across my academic and industry work, I have been fortunate to study these fundamental questions and to apply what I learned across fields, including video editing, autonomous driving, dynamical systems and cell foundation models.

Experience

  1. 2025 – now

    NLP Research Engineer, Riverside

    Built agentic and ML pipelines that automatically edit recorded episodes.

  2. 2024 – 2025

    Research Scientist, IBM Research

    Quantified confidence in transcriptomic foundation models.

  3. 2020 – 2025

    PhD in Computer Science, Hebrew University of Jerusalem

    Advised by Dr. Mor Nitzan. Machine learning for dynamical systems and single-cell biology. Council of Higher Education and CIDR PhD fellowships.

  4. 2019 – 2020

    Research Scientist, Harvard University

    Reconstructed tissue structure from single-cell data with optimal transport (NovoSpaRc).

  5. 2018 – 2019

    Algorithm Engineer, Mobileye

    Built real-time deep learning detection and scene-understanding models for autonomous vehicles.

  6. 2016 – 2018

    MSc in Computer Science and Computational Biology, Hebrew University of Jerusalem

    Advised by Prof. Nir Friedman. Adapted single-cell RNA-seq to yeast, both technologically and computationally. 2nd in class, with an exchange at the University of Toronto.

  7. 2016

    Research Scientist, Broad Institute of MIT and Harvard

    Experimented with single-cell RNA-seq methods and their analysis in yeast, and designed a CRISPR combinatorial perturbation library.

  8. 2012 – 2015

    BSc in Computer Science and Computational Biology, Hebrew University of Jerusalem

    Quantified how much of the variance in yeast stress response is explained by cell-cycle variation. Magna cum laude, Dean’s Award.

Selected publications

* equal contribution. Full list on Google Scholar.

Foundation models for biology

Pretraining loss landscape over gene expression space: low for real cells, high for shuffled and interpolated samples

Toward a coherent virtual cell model: probing biological world-model coherence in transcriptomic foundation models

Noa Moriel, Yishai Shimoni, Michal Rosen-Zvi, Michael M. Danziger

NeurIPS 2025 workshop AI for virtual cells and drug discovery (AI4D3)

Can a transcriptomic foundation model tell a real cell from a shuffled one? We propose a model-agnostic test based on synthetic samples and pretraining loss. Models separate real from shuffled cells and show loss barriers between distant cell types, but a coherent world model is far from universal.

Paper PDF IBM Research

Machine learning for dynamical systems

Single-cell and spatial genomics

TACCO annotation transfer overview

TACCO unifies annotation transfer and decomposition of cell identities for single-cell and spatial omics

Simon Mages*, Noa Moriel*, …, Johanna Klughammer, Aviv Regev, Mor Nitzan

Nature Biotechnology 2023

A framework that transfers annotations from reference data to single-cell and spatial omics at scale, supporting expression decomposition, cell fate prediction and recovery from read dropout. We used it to map spatially defined functional units in colorectal cancer (eLife 2025).

Paper Code Colorectal cancer paper

Teaching

Hebrew University of Jerusalem

Beyond research

I have a precious little daughter, Naya.

Sports keep me sane: I enjoy running, swimming and hiking. I love experimenting with arts, including woodworking, pottery, glass art and printing, and with regrowing all kinds of plants.

These are my awesome brothers: postdoc Avraham Moriel, MD PhD Nadav Moriel, and (fresh scholar) Gilad Moriel.